Author(s): S. Geetha and Aruna Devaraj
Acute oral toxicity of organic grapes produced by microbial fertigation and foliar spray of panchagavya was evaluated in albino rats. In the present study, albino wistar rats were administered Vitis vinifera fruit extract orally with dosages of 200, 400 and 800 mg Kg-1 body weight. Mortality, body weight and haematological parameters were observed for 7 days after treatment. Effect of methanolic extract of Vitis vinifera on pylorus ligated rats and HCl – Ethanol induced gastric lesion in rats was studied simultaneously. The methanol extract of Vitis vinifera was found to be non toxic and safe as oral intake. The methanol extract of organic grapes was found to possess a protective effect against gastric ulcer and acidity.