Author(s): Bhuvaneswari Santharam, Divya V V and Thangathirupathi A*
Ageratum conyzoides Linn. (Asteraceae) is a soft hairy annual weed with powerful traditional uses. Aqueous, ethyl acetate and ethanolic extracts were prepared from the whole plant of A. conyzoides (L.). Urolithiasis was induced by using 5 % ethylene glycol in wistar albino rats. Rats were treated with different extracts of A. conyzoides (L.) at a dose level of 500 mg/kg bwt while Calcuri at same dose level was used as standard. The results of the study proved that all the plant extracts significantly reduced calcium and oxalate concentration in the excreted urine and the deposition of the same in the kidney, while the highest reduction in the calcium and oxalate in the urine and kidney was noted with the ethanol extract. Preliminary phytochemical analysis revealed the presence of a number of phytochemical constituents in different extracts which may help in the identification of plant. The present result advocates the antiurolithiatic activities of different extracts of the plant.