Author(s): Balamurugan K and Natarajan P *
Weaver ant Oecophylla smaragdina (OS) belongs to family Formicidae has been used by traditional village people, and also as the indigenous medicine. The present study was planned to induce rheumatoid arthritis in Wistar albino rats by complete Freund’s adjuvant in the dose of 100µl. The ethanol extract of Oecophylla smaragdina (EEOS) was administered by the oral dose of 200mg/kg, 400mg/kg, for a period of 24 days duration. The Biochemical parameters, haematological parameters, and histopathology of the joint tissue were studied. The Oecophylla smaragdina (OS) extract attenuated the rheumatoid arthritis factors induced by complete Freund’s adjuvant by the dose-dependent manner. The current study concludes that EEOS extract of both concentrations provides a significant effect of anti-arthritic effects.