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ISSN (Online) : 2277-4572

ROLE OF APIGENIN ON GEMCITABINE-INDUCED LIPID PEROXIDATION

Abstract

Author(s): Sarbani Dey Ray *

The present study explores the role of apigenin on gemcitabine-induced lipid peroxidation. The work was carried out in vitro and goat liver was used as model lipid source. Estimation of malondialdehyde and reduced glutathione of the tissue content were used as marker for the model. The results showed that gemcitabine has the ability to induce lipid peroxidation to a significant extent and it was also found that apigenin has the ability to suppress the gemcitabine-induced toxicity.