ISSN (Online) : 2277-4572
Author(s): Srinivas Sangu, Aparna Vema, Rajkamal Bigala, Saikiran Gadipalli
Quinoline derivatives are reported to have anti microbial, anti inflammatory, analgesic and anti cancer activities. The incorporated oxymethyl carbamide at 8th position of the quinoline ring was found to influence the biological activities of the molecules with this some of new quinolinyl oxymethyl azetidinones and quinolinyl oxymethyl azetidinones and thiazolidinones were synthesized from 8-hydroxy quinoline through (quinolin-8-yl-oxy) acetyl hydrazide intermediates. All the synthesized compounds were characterized by IR, H1NMR spectral data and evaluated for their anti microbial activity.
