ISSN (Online) : 2277-4572
Author(s): Majumder Pulak
Over the years there has been a great revolution in drug delivery technologies. Virosomes drug delivery systems are an example of the various novel drug delivery systems available. A virosome is a drug or vaccine delivery mechanism consisting of unilamellar phospholipid bilayer vesicle incorporating virus derived proteins to allow the virosomes to fuse with target cells. Virosomes are not able to replicate but are pure fusion-active vesicle. These are reconstituted viral envelopes that can serve as vaccines and as vehicles for cellular delivery of macromolecules. The prospect of drug delivery and targeting using virosomes is an interesting field of research and development. Because virosomes are biocompatible, biodegradable, nontoxic, and non-autoimmunogenic, attempts have been made to use them as vaccines or adjuvants as well as delivery systems for drugs, nucleic acids, or genes for therapeutic purposes. The success of virosomal drug delivery depends on the methods used to prepare the encapsulated bioactive materials and incorporate them into the virosomes, as are characterization and formulation of the finished preparation. This article gives an insight of virosomes as a newer method of drug delivery. This article gives an insight of hydrogels and virosomes as a newer futuristic tool.
