Author(s): Qazi Rais Ahmed*, Sapna Goyal, Narendra Gupta, Raj Bhadur Kamal, Shikky Garg
The best early evidence of a description of the symptoms of diabetes in the world's literature is recorded in the Ebers Papyrus that Diabetes Mellitus is characterized by chronic hyperglycemia with disturbances of carbohydrate, fat, and protein metabolism result in from defects in insulin secretion, insulin action, or both which affect the respiratory system also. So we decided to study the effects of diabetes mellitus on pulmonary parameters. In this study a group of 50 apparently healthy control subject of both gender and 50 Diabetic patients of both gender were randomly selected with age ranging from 19-68 years. The Diabetic patients were matched with control group in terms of age, height, weight and BSA and BMI. Spirometry was performed on an electronic spirometer (spiro exel) according to American Thoracic Society and results were compared by a student t-test (2-tailed). Diabetic patients showed a significant decrement in the Forced Vital Capacity (FVC %) and Peak Expiratory Flow Rate (PEFR %) relative to their matched controls. However, there were no significant difference in the Forced Expiratory Volume in one Second (FEV1%) and Forced Expiratory Ratio (FEV1 / FVC %) between the groups We conclude that pulmonary parameters in diabetic patients there is decrement in FVC% and PEFR%, as compared to controls. which indicate restrictive pattern of lung function impairment.