Author(s): Carlos Manuel Escaño Bautista*
Background: The progression of chronic kidney disease is associated with thyroid dysfunction. The thyroid hormonal disturbances that are associated with chronic kidney disease are subclinical hypothyroidism and euthyroid sick syndrome.
Method: To characterize patients with chronic kidney disease on hemodialysis according to thyroid hormonal alterations.
Results: Retrospective, descriptive study in the Nephrology service of the Hospital Clínico Quirúrgico “Hermanos Ameijeiras” of patients with chronic kidney disease on hemodialysis in the period from November 1 to December 30, 2018. Male sex predominated (50.8%); age 45 years-64 years (42.4%); white skin color (40.7%); time on hemodialysis greater than 5 years (54.2%) and euthyroid sick syndrome (40.7%), followed by subclinical hypothyroidism (30.5%). There were significant differences in the predominant thyroid alterations with the following variables: albumin (p=0.016), hemoglobin (p=0.017), urea (p=0.008) and time on hemodialysis (p=0.007). There was a significant correlation between TSH and time on hemodialysis, urea (r=0.382, r=0.257); between T3 and time on hemodialysis, urea, albumin (r=-0.385, r =-0.413, r=0.493); between T4 and albumin (r=0.381).
Conclusion: The most frequent thyroid hormonal alterations were the euthyroid sick syndrome, followed by subclinical hypothyroidism. Albumin and hemoglobin levels were lower in patients with thyroid disorders. The urea value and time on hemodialysis were higher in patients with thyroid disorders.