Author(s): N. Junior Sundresh*, S. Narendran, R. Ramesh, Kesavjagadeesan, N. Nasarareddy
Worldwide, Diabetic Foot Ulcers are a major medical, social and Economic Problem and are the Leading Cause of Hospitalization for most of the Patients with Diabetes. Diabetic foot is the most common complication of Diabetes. Diabetic foot ulcerations and infections are one of the leading causes of mortality and morbidity, especially in the developing countries. The Indian diabetic population is expected to increase to 57 Million by the year 2025. Mostly, The Diabetic foot infections are mixed bacterial infections and the proper management of these infections requires an appropriate antibiotic selection, based on the culture and the antimicrobial susceptibility testing results. A prospective study was carried out on 50 diabetic patients with foot ulcers for a period of 6 months from January 2013 to June 2013 admitted at Rajah Muthiah Medical College and hospital. A total of 122 organisms were isolated and an average of 1.22 isolates per case was reported. Poly microbial nature was observed and gram negative (52.45 %) organisms dominated the positive (47.54 %) in case of number of organisms isolated. The most frequent bacterial isolate was Staphylococcus aureus (39.34 %) and E. coli (23.77 %). Antibiotic sensitivity pattern of the isolates was discussed in detail. Neuropathy (29 %) and peripheral vascular disease (27 %) were the common clinical characteristics of the patients. Staphylococcus was the most frequent bacterial isolate in this study followed by E. coli. Diabetic foot ulcers are poly microbial in nature. Beta lactam/ beta lactamase inhibitor combinations, vancomycin, fluroquinolones were the suitable choices for the empiric antibiotic therapy found by this clinical and bacteriological study.