Author(s): Swagata Chakraborty*, Apala Sengupta, Abichal Chattopadhyay
Dyslipidemia in type II diabetes mellitus in term of meda du??i in prameha also introduces Medouja-dusti. Due to faulty lipid metabolism, serum Lipoprotein A gets increased which can be interpreted as Medouja-dusti. The rationale of this study was to detect Medouja-dusti and medadusti in the patients of prameha in terms of serum Lipoprotein A along with lipid profile evaluating the efficacy of pippali churna. This study was a prospective, randomised and control clinical study having 2 groups, 30 patients each; group A (experimental) was treated with Pippali and group B (control) with Haridra. Patients were selected from OPD and IPD of- Institute Of Post Graduate Ayurvedic Education and Research at Shyamadas Vaidya Shastra Peeth Hospital, Kolkata, irrespective of sex and religion as per subjective criteria of prameha, Oja visramsa and oja vyapat and objective criteria of FBS, PPBS, HbA1C, serum triglyceride, total cholesterol and Lipoprotein A following exclusion and inclusion criteria. Pippali churna had been administered orally at a dose of 3 gm/day at divided doses. Before and after treatment data had been assessed statistically. Group A had showed highly significant results (p < 0.001) in all the objective parameters where group B had showed result as highly significant (p < 0.001) in FBS, PPBS, Total Cholesterol and TG, significant (p < 0.1) in HbA1C and non-significant in Lipoprotein A. Improvement of subjective criteria and unpaired ‘t’ test proved group A as highly significant. Pippali reduced the lipids along with lipoprotein A simultaneously normalising blood sugar by its Rasapanchaka proving itself as an excellent remedy medadusti and Medouja-dusti in prameha.