Author(s): Nayak Shreya and Sanjay Pai P. N.*
A rapid, reliable, sensitive UV-spectrophotometric method has been developed for the determination of Balofloxacin in bulk and marketed tablet dosage form using 1 % w/v of ferrous sulphate as a chromagenic / complexing agent. The yellow colour complex formed by complexation of iron (II) with balofloxacinwas stable and was measured for absorbance at its λ max of 357 nm. The Beers law was obeyed at the concentration range of 10-100 µg / ml with good correlation coefficient of 0.9992. The method was optimized and validated for linearity, accuracy and precision. The proposed method is simple and can be routinely used for the estimation of balofloxacin in its tablet formulations.