Author(s): Sriram A *, Dhanapal C.K
To observe and document the drug use pattern in hospitalized diabetic patients. To determine the choice of therapy based on age, gender, complications, duration of the disease. To find out the commonly occurring adverse drug reactions associated with antidiabetics. The present study involves prospective observational study for patients with diabetes. The methodology involves collection and documentation of patients medical and medication history, blood glucose levels, and duration, choice of therapy with diabetes. During the period of study, a total of 143 cases were collected and reviewed, among that 91% cases were type 2 diabetes mellitus and 9 % cases were type 1 diabetes mellitus. In this study females were higher in range than males. Most of the patients were with the age group of 41 to 60 followed by the age group 61 to 70 was affected by diabetes mellitus. The overall study shows Insulin was used more in most of the prescriptions for both single as well as doublet therapy. Next, to that Metformin was used as first line agent all type2 diabetes patients. Sulfonylureas such as Glimepiride Glibenclamide were used as second line agent. Oral anti-diabetic drugs still dominate the drug prescribing pattern, but there was a little change in the study towards the use of Insulin preparations in the management of Type 2 diabetes mellitus because of the severe diabetic level and insulin deficiency. Insulin preparations were found to be more effective than oral antidiabetics for hospitalized patients.