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ISSN (Online) : 2277-4572

EXPLORING THE PROETECTIVE ROLE OF WATER EXTRACT OF SPIRULINA PLATENSIS ON GEMCITABINE-INDUCED LIPID PEROXIDATION USING COMMON LABORATORY MARKERS

Abstract

Author(s): Sarbani Dey Ray*

The present study was designed with an aim to explore the protective role of water extract of Spirulina platensis on gemcitabine-induced lipid peroxidation. The work was carried out in vitro and goat liver was used as model lipid source. Two common laboratory markers such as malondialdehyde and reduced glutathione were used for the model. The results showed that gemcitabine has the ability to induce lipid peroxidation to a significant extent and it was also found that water extract of the Spirulina platensis has the ability to suppress the gemcitabine-induced toxicity.