ISSN (Online) : 2277-4572
Author(s): Shailima RD Vardhini*
Proteins are the biomolecules which have a vital role in the human beings. The biological activity of the proteins is based on the structures of the proteins. One of the structural importance of the proteins is making the proteins a validate drug targets. In the present article DHFR enzyme structure was predicted and validated. Further the experiment proceeds by performing the docking studies of this modeled structure with Breast cancer inhibitors giving a scope for one drug many cancer concept. The docking results were very promising with the H- bond interactions between Gly118, Gly21, Lys 56, Thr 147 and Asp 22.
