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ISSN (Online) : 2277-4572

PACLITAXEL INDUCED LIPID PEROXIDATION: ROLE OF WATER EXTRACT OF SPIRULINA PLATENSIS

Abstract

Author(s): Supratim Ray *, Sarbani Dey Ray

The present study showed the free radical scavenging activity of water extract of Spirulina platensis on paclitaxel-induced lipid peroxidation. This in vitro work was carried out with goat liver as lipid source using malondialdehyde and 4-hydroxy-2-nonenal as model markers. The findings suggest that paclitaxel could induce lipid peroxidation to a significant extent and it was also found that water extract of the Spirulina platensis has the ability to suppress the paclitaxel-induced toxicity.