Author(s): Bin Wang, Cheng Gui Zhang, Peng Fei Gao, Xiu Mei Wu*, Yu Zhao*
Nidus vespae is a drug derived from insects that is commonly used in traditional Chinese medicine (TCM). No systematic review has previously been made about this drug. This paper summarizes previous investigations about the 49 identified chemical constituents and clinical application of Nidus vespae, and explores its pharmacological mechanism of treating disease. Nidus vespae has been reported to be effective in the treatment of rheumatoid arthritis and psoriatic arthritis, intractable skin diseases, dental disease, rhinitis, respiratory disorders, cervical erosion etc. Nidus vespae can be used alone or in combination with other drugs and compounds for a wide range of clinical applications. The objective of this review is to provide a comprehensive reference for further development and utilization of Nidus vespae.