STUDY OF LEVELS OF MICROALBUMINURIA IN CORONARY ARTERY DISEASE AND DIABETES MELLITUS

Abstract

Author(s): Suvarna Tryambak Jadhav*, Ajit V Sontakke, Bipin M Tiwale, Nilima Patil, Smita Patil

Coronary Artery Disease (CAD) leads to Angina and Myocardial Infarction (MI). Premature mortality on Coronary Heart Disease (CHD) is more common in diabetic atherosclerosis. In the present study serum level was Microalbuminuria estimated in patients of CAD with DM, CAD without DM, DM without CAD and CAD with DM and other risk factors compared to healthy normal subjects. The level of Microalbuminuria was significantly increased in all four groups of patients as compared to control group. On the basis of our results we conclude that microalbuminuria is a marker of vascular damage and thus is an early finding in atherosclerosis. Microalbuminuria is associated with wide spread abnormalities in the vasculature that may manifest as altered vascular reactivity and endothelial dysfunction.