Author(s): Raja Reddy P, Jayarama N, Shashidhar KN
Study was planned to evaluate the relationship among glycated hemoglobin (HbA1C) and lipid profile in type 2 diabetic population. A total of 750 type 2 diabetic patients (males, 493; females, 257; mean age, 55.65 ± 12.47) were included in our study. Venous blood samples were collected from all the subjects after at least 8 hours fasting. The sera was analyzed for HbA1c, fasting blood glucose (FBG), total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-c) and low-density lipoprotein cholesterol (LDL-c). The statistical analysis was done by SPSS. The mean HbA1 C was 9.18 %. Female patients showed more mean values for FBG (155 ± 75), TC (189 ± 103), TG (190 ± 96), LDL-c (106 ± 39) and HbA1C (9.65 ± 9.65). The HbA1 C showed significant positive relationship with TC (r = 0.144) and LDL-c (r = 0.086). It was concluded from the results of this study that HbA1 C can be used as a predictor of dyslipidemia used as a preventive measure for the development of cardiovascular disease in type 2 diabetes and study also suggested relative risk of cardiovascular disease is higher in diabetic women compared to diabetic men.